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The aim of this paper is to examine variations in the combination of social roles during times of social change. We specify a latent class approach to examine role configurations for individuals in their early 30s, establishing a typology of how work- and family-related roles combine within individuals born 12 years apart and examine their antecedents. Drawing on data collected for two British Birth Cohorts born in 1958 (N = 10,706) and 1970 (N = 11,005), we provide empirical evidence of both consistency and change in life course patterns. Findings are discussed in terms of destandardization, differentiation, and individualization of the life course in times of social change and their implications for family research within a life course perspective.